People/person profiles with featured images, positions, pillars, and affiliations.
Research Bio: Dr. Raulet’s laboratory is dedicated to understanding recognition by natural killer cells and T cells, and is developing approaches to mobilize NK cells therapeutically against cancer. He is a world expert in cancer immunology and NK cell biology. His laboratory has made fundamental contributions to our understanding of both recognition by NK cells…
Research Bio: The goal of Dirk Hockemeyer’s research is to shed light on the key functions of telomeres and telomerase in tissue homeostasis, tumorigenesis and aging. Telomeres are the repetitive DNA sequences at the end of linear eukaryotic chromosomes that allow a cell to distinguish the natural chromosome end from aberrant DNA breaks. Telomeric DNA…
Research Bio: Thomas Mann’s research interests are at the intersection of signal transduction and T cell differentiation. The cardinal feature of the adaptive immune system is formation of a response to specific antigens. Recognition of an antigen for the first time causes T cells to proliferate and differentiate into many specialized states. However, antigen exposure…
Research Bio: As an organism ages, its proteins face an increasing severity in the challenges they receive from extrinsic and intrinsic environmental perturbation. Chaperones become dysregulated, while the degradation machineries stop working properly. The protein accumulates damage and starts to misfold. At this point, the cell needs to mount a response to restore its homeostasis;…
Research Bio: Robert Saxton is an Assistant Professor of Molecular and Cell Biology and Chemistry studying molecular mechanisms of immune cell signaling in the context of tissue inflammation and repair. The Saxton Lab uses a combination of protein engineering, structural biology, and functional genomics to interrogate immune cell communication, with the goal of developing new…
Research Bio: Ellen Robey is a Professor of Immunology and Molecular Medicine. The Robey Lab is interested in how signaling pathways control cell fate decisions. By using T cell development and immune responses in the mouse as model systems, they can take advantage of the powerful genetic approaches available in the mouse, while learning about…
Daniel A. Portnoy is a microbiologist and immunologist who studies the cellular and molecular mechanisms of host–pathogen interactions. He is best known for groundbreaking research on Listeria monocytogenes, which revealed how intracellular pathogens invade, replicate, and evade immune defenses. His lab pioneered genetic and molecular approaches to study innate immunity, including the discovery of pathways…
Research Bio: Lin He is the Thomas and Stacey Siebel Distinguished Chair professor and a professor in MCB department. Lin He is also a Biohub investigator in Chan-Zuckerberg Initiative. While proteins are the structural and functional unit of living cells, only ~2% of mammalian genome contains protein-coding elements. It is increasingly clear that the ~98%…
Michel DuPage is an Assistant Professor of Immunology and Pathogenesis. The DuPage lab is focused on examining the interface of the immune system and cancer. They intersect the fields of cancer biology, immunology, and epigenetics with the goal to strengthen our own immune defense mechanisms against our own cancers. To do this, they aim to…
